The researchers used results from a similar German study to draw comparisons and identify the common genetic variations that led to an increase in the risk for heart disease. They found that changes in the DNA on the chromosomes were responsible for increased risk of developing coronary artery disease and heart attacks. The researchers identified not one or two but six different genetic variations, each linked to a higher risk.
The findings by Dr. Samani and team confirm those of a study earlier this year in which researchers found that mutations on another chromosome increased the risk of heart disease. “Carrying one copy of the genetic change increased the chance of developing heart disease by at least 20 percent, while two copies increased the risk by more than 40 percent” Dr. Samani said.
Tags: CHD, Dr. Samani, DNA
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