Certain cholesterol-reducing drugs appear to damage mitochondria, the tiny power stations inside living cells.
Aches and cramps
When the researchers tested various statins, which are widely prescribed for lowering cholesterol levels in the blood by inhibiting a key enzyme involved in cholesterol synthesis, they found that three of them - fluvastatin, lovastatin and simvastatin - were toxic towards mitochondria. 'Patients have reported muscle aches and cramps as a side effect of some statins and this could be one reason,' Mootha told Chemistry World. 'This clinical hypothesis could have huge implications worldwide.'
Tags: mitochondria, fluvastatin, lovastatin, simvastatin
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